Developing Novel Monoclonal Antibody Therapeutics

TrueBinding Inc. is a clinical stage biotherapeutic company creating new and exciting molecules for applications in neurodegenerative and metabolic diseases, stroke, oncology and other areas with great unmet medical need.

Revolutionizing Patient Care

TrueBinding is optimizing patient care through its revolutionary pipeline of monoclonal antibody therapeutics, providing targeted treatments for a diverse range of diseases and medical conditions. By harnessing the power of our platform technology, we rapidly develop and deliver highly specific and effective monoclonal antibodies, ushering in a new era of precision medicine that holds the promise of improved patient outcomes and enhanced therapeutic options.

Accelerating Biopharmaceutical Innovation

TrueBinding's contract development and manufacturing services offer unparalleled benefits for clients in the biopharmaceutical industry. By leveraging our advanced technology and expertise, our teams can accelerate the development process, ensuring rapid and efficient production of high-quality monoclonal antibodies, ultimately enabling clients to bring their innovative therapies to market faster and more cost-effectively.

TB006 Expanded Access Program

Granting access to investigational medications, the Expanded Access Program (EAP) for TB006 offers a compassionate approach to providing potential benefits to patients who have exhausted all other alternatives combating Alzheimer’s Disease.

Completion of Phase 1b/2a Clinical Trial for Alzheimer's Disease

Topline data from a one-month TB006 treatment regimen shows improvements in Clinical Dementia Rating-Sum of Boxes (CDR-SB) in patients, indicating the potential of slowing or reducing clinical decline. Key secondary endpoints were consistent with the primary findings that TB006 improved cognition and function in patients

Latest News

May 26, 2024

The FDA has renewed the Expanded Access Program (NCT05959239) for TB006 in treating dementia and Alzheimer's disease. This renewal allows existing patients to continue receiving TB006 outside of traditional clinical trials and offers hope for patients seeking alternative treatment options.

July 9, 2024

The FDA has approved TrueBinding to proceed clinical trials for TB006, a new therapeutic candidate for treating adult autism spectrum disorder (ASD). The clinical trials (NCT06500637) will assess TB006’s safety and efficacy, offering hope for new, effective treatment options for those with ASD and potentially improving their quality of life.

Nov 18, 2024

TrueBinding has cleared an FDA IND application for TB006 for potential disease modification of Parkinson’s Disease. A multi-center, placebo-controlled, Phase 2A trial (NCT) of TB006 in the U.S. will be evaluating the safety and efficacy of this treatment in patients with early to mild Parkinson’s Disease.