Therapeutics from bench to clinic begins at TrueBinding - your local CDMO

Research and Development

  • DNA Sequence Analysis, Cloning and Transfection

  • Pool Selection, Cloning and Selection of Top Clones

  • Creation of RCB and Biosafety Testing

  • Cell Line Stability Studies

  • Bioreactor Clone Screening

  • Scale-up and Upstream / Downstream Process Development

  • Analytical Method Development and Qualification

  • Early and Late Stage Formulation Development

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Vivarium Services

  • IACUC Protocols, Drafting, Renewals and Amendments

  • Animal Ordering, Receiving, Housing, and Breeding

  • MRI/PET for Mice and Rats, Rodent Ultrasound

  • Bioluminescence and Fluorescence Imaging

  • Basic as well as Invasive Surgeries

  • Human Disease Animal Modeling and Optimization

  • PK/PD studies in Mice and Rats

  • Safety and Toxicology studies in Mice and Rats

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cGMP mAbs Manufacturing

  • MCB and WCB Cell Banking and Testing

  • 50L, 200L or 500L SUB Production Bioreactors

  • AKTA Purification Platform

  • Viral Inactivation and Viral Filtration

  • Ultrafiltration and Diafiltration, Formulation

  • Bulk Drug Substance Storage

  • In-Process and Release Analytical Testing

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Media and Buffer Manufacturing

  • Raw Material Testing

  • 1L to 3000L Media and Buffer Manufacturing

  • Cold Storage Available

  • QC Analytical Testing

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Histology and Imaging Core

  • Wet tissue processing, embedding, sectioning

  • Single & Multiple IHC/IF staining. 1 or 2 color immunohistochemistry staining (DAB, red chromogen). 1, 2, 3-color immunofluorescence plus Dapi counter staining.

  • Special stains and assays: H&E, Oil red O (fat), Periodic acid

    Schiff (PAS), Masson’s Trichrome, Toluidine blue (mast

    cells), Tunnel assay

  • Bright field whole slide scan

  • Confocal microscopy (20x, 40x, 63x 4 channel images, 3D movies)

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Clinical Drug Product (DP) Logistics

  • Clinical Label Design, Printing, Application, and Label Inspection

  • DP Packaging

  • Monitored and Regulated DP Storage

  • Qualified Worldwide DP Distribution

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cGMP Training and Audit Preparation

  • Basic cGMP Best Practices

  • Cleanroom Gowning Training

  • Cell Culture Expansion Training

  • Aseptic Processing Training

  • Single-Use Bioreactor Training

  • Purification, Viral Inactivation, Viral Filtration, UFDF Training

  • FDA Audit Preparation

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Antibody Discovery Services

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