Vivarium Services
TrueBinding Vivarium is a leading provider of comprehensive services for animal research and experimentation. We offer expertise in IACUC protocols, animal ordering, housing, and high standards of care. With round-the-clock animal health surveillance, we ensure the well-being of our animals. Our facility provides complete veterinarian oversight, including treatment, care, and specialized procedures such as animal dosing and blood sampling.
Equipped with advanced imaging capabilities, including MRI/PET, bioluminescence, and fluorescence imaging, we support cutting-edge research. Our expertise extends to lung function measurements, rodent ultrasound, and blood pressure monitoring. We possess the RS-2000 Biological System for precise irradiation, and our surgical capabilities include basic and invasive procedures like stereotaxic surgeries and injections.
TrueBinding Vivarium excels in human disease animal modeling, PK/PD studies, safety and toxicology evaluations, as well as mice breeding. We offer comprehensive services such as animal disease scoring, metabolic cage studies, and behavioral experiments using various equipment. With a commitment to client success, we provide training for all our activities. Our mission is to facilitate scientific research by providing top-notch services, expertise, and state-of-the-art equipment.
Testing
Von Frey- testing analgesia, nociception, neuro-pathologies and post-operative pain (BIO-EVF4-S and elevated metal mesh stand, BIOSEB)
OCT SPECTRALIS for ophthalmic imaging (HEIDELBERG ENGINEERING)
Controlled Cortical Impactor (for Traumatic Brain Injury modeling)
Spinal Cord Injury Impactor
Blood Pressure (CODA Non-Invasive Blood Pressure System, Kent Scientific CORP.)
Pressure Volume Millar Catheters (AD Instruments)
Stereotaxic instruments for surgery (Stoelting)
Glucometers for Glucose test; GTT/ITT (Glucose201, HEMOCUE)
Behavior-Rotarod test (MAZE Engineers)
Water maze and Barnes Maze
MPVS Ultra Foundation Systems, transonic for cardiovascular (AD Instruments)
Basic Animal Care
High Standards of Basic as well as Specialized Animal Care
Round the Clock Animal Health Surveillance Program
Complete Veterinarian Oversight, treatment and care
Administrative
Help with IACUC Protocols, Drafting, Renewals and Amendments
Animal Ordering, Receiving and Housing
Animal Disease Modeling
Oncology: Liver Cancer, Pancreatic Cancer, Breast Cancer, Thyroid Cancer, Brain Cancer
Neurodegenerative Diseases: Alzheimer’s Disease, Stroke, Parkinson Disease, ALS, Huntington’s Disease, Spinal Cord Injury, Traumatic Brain Injury, Aging Studies, Multiple Sclerosis (EAE)
Inflammatory Diseases: Ashma, Lung Fibrosis, COPD, RACIA, Prostatitis, Sepsis, Glomerulonephritis, Inflammatory Bowel Disease, Rheumatoid Arthritis, Cystic Fibrosis
Autoimmune Diseases: Psoriasis, Lupus
Metabolic Diseases: Diabetes, Hypertension
Kidney Diseases: Kidney Fibrosis, Chronic Kidney Disease, Polycystic Kidney Disease
Liver Pathologies: NASH, HCC
Cardiovascular Diseases: Atherosclerosis, Heart Fibrosis, Heart Failure, Congestive Heart Failure, Deep Vein Thrombosis
Equipment
Capabilities
Mouse Study Designs
Non-GLP preclinical safety tox
Efficacy
PK/PD studies in Mice and Rats
Behavioral Study
Surgery
Target Validation
Mouse Services
Animal Dosing via all routes
Animal Blood Sampling via all routes
Humane Euthanasia and Complete Necropsy
Mice Breeding Services
Mouse CSF harvest (before perfusion)
Imaging
MRI/PET (NanoScan PET/MRI 3T, Mediso)
Ultrasound (Vevo3100, Vevo LAZR-X, VISUALSONICS)
Irradiation (RS-2000 Biological System, RAD SOURCE TECH.)
IVIS SPECTUM CT(PerkinElmer)
EchoMRI Body composition analyzer (EchoMRI)
15 min to cGMP Facility
15 min to SFO
30 min to Oakland Airport
30 min to Downtown San Francisco
Vivarium Services are located in Foster City, CA
Facilities
Innovive IVC Racks (Individual Ventilated Caging Systems) for Mice and Rats
Mouse/Rat metabolic cages
Biosafety and Fume Hoods
Dissection Microscopes
Surgery equipment and accessories
Radio Isotope Use station with lead shields and pits
Specialized Mouse Techniques
• MRI/PET for Mice and Rats (including Isotope ordering, receiving, use and disposal)
• Bioluminescence and Fluorescence Imaging
• Lung Function Measurements in Pulmonary Disease
• Rodent Ultrasound
• Blood Pressure Measurements for Mice and Rats
• Using RS 2000 Irradiator, Irradiation of rodents and cells
• Basic as well as Invasive Surgeries including Stereotaxic Surgeries and Injections
• Human Disease Animal Modeling and Optimization
• Animal Disease Scoring and measurements (e.g Tumors in oncology, foot and paws in arthritis etc.)
• Metabolic Cages studies in mice and rats
• GTT/ITT tests in rats and mice
• Behavioral experiments including use of Rotarods, Water Maze, Dry Maze etc.
Get in touch.
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